BDBM10775 3-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-inden-5-yl N-methyl-N-propylcarbamate::Aminoindan deriv. 19c::N-propargylaminoindan 19c

SMILES CCCN(C)C(=O)Oc1ccc2CCC(N(C)CC#C)c2c1

InChI Key InChIKey=DOCKMKZFEVDKQI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10775   

TargetAmine oxidase [flavin-containing] A(Rat)
Teva Pharmaceutical Industries

LigandChemical structure of BindingDB Monomer ID 10775BDBM10775(3-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-ind...)
Affinity DataIC50: 5.60E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Teva Pharmaceutical Industries

LigandChemical structure of BindingDB Monomer ID 10775BDBM10775(3-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-ind...)
Affinity DataIC50: 9.20E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Teva Pharmaceutical Industries

LigandChemical structure of BindingDB Monomer ID 10775BDBM10775(3-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-ind...)
Affinity DataIC50: 1.00E+6nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed