BDBM10777 3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl N,N-dimethylcarbamate::Aminoindan deriv. 21a::N-propargylaminoindan 21a

SMILES CN(C)C(=O)Oc1cccc2CCC(NCC#C)c12

InChI Key InChIKey=HVCOWYUWVWKCLH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10777   

TargetAcetylcholinesterase(Human)
Teva Pharmaceutical Industries

LigandPNGBDBM10777(N-propargylaminoindan 21a | 3-(prop-2-yn-1-ylamino...)
Affinity DataIC50: 2.50E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Teva Pharmaceutical Industries

LigandPNGBDBM10777(N-propargylaminoindan 21a | 3-(prop-2-yn-1-ylamino...)
Affinity DataIC50: 2.80E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10777(N-propargylaminoindan 21a | 3-(prop-2-yn-1-ylamino...)
Affinity DataIC50: 1.00E+6nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10777(N-propargylaminoindan 21a | 3-(prop-2-yn-1-ylamino...)
Affinity DataIC50: 1.00E+6nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed