BDBM10783 1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-yl N,N-dimethylcarbamate::Aminoindan deriv. 23a::N-propargylaminoindan 23a

SMILES CN(C)C(=O)Oc1cccc2C(CCc12)NCC#C

InChI Key InChIKey=ACQQSVLNYFFGER-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 10783   

TargetAcetylcholinesterase(Human)
Teva Pharmaceutical Industries

LigandPNGBDBM10783(N-propargylaminoindan 23a | 1-(prop-2-yn-1-ylamino...)
Affinity DataIC50: 53nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10783(N-propargylaminoindan 23a | 1-(prop-2-yn-1-ylamino...)
Affinity DataIC50: 53nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10783(N-propargylaminoindan 23a | 1-(prop-2-yn-1-ylamino...)
Affinity DataIC50: 260nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10783(N-propargylaminoindan 23a | 1-(prop-2-yn-1-ylamino...)
Affinity DataIC50: 260nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Teva Pharmaceutical Industries

LigandPNGBDBM10783(N-propargylaminoindan 23a | 1-(prop-2-yn-1-ylamino...)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of recombinant human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10783(N-propargylaminoindan 23a | 1-(prop-2-yn-1-ylamino...)
Affinity DataIC50: 8.60E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed