BDBM10787 Aminoindan deriv. 25a::N,N-dimethyl-1-{[3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl]oxy}methanethioamide::N-propargylaminoindan 25a

SMILES CN(C)C(=S)Oc1ccc2CCC(NCC#C)c2c1

InChI Key InChIKey=CDQZBZUAACBTIU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10787   

TargetAmine oxidase [flavin-containing] B(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10787(N,N-dimethyl-1-{[3-(prop-2-yn-1-ylamino)-2,3-dihyd...)
Affinity DataIC50: 9.80E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10787(N,N-dimethyl-1-{[3-(prop-2-yn-1-ylamino)-2,3-dihyd...)
Affinity DataIC50: 1.30E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Teva Pharmaceutical Industries

LigandPNGBDBM10787(N,N-dimethyl-1-{[3-(prop-2-yn-1-ylamino)-2,3-dihyd...)
Affinity DataIC50: 5.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed