BDBM107898 CHEMBL373487::US8604218, 1.049

SMILES Cc1n[nH]c2ccc(NC3CCCN(Cc4ccccc4)C3)cc12

InChI Key InChIKey=RWIWATQFHWUZHC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107898   

TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL

LigandBDBM107898(CHEMBL373487 | US8604218, 1.049)Copy SMILESCopy InChI

Affinity DataIC50:  150nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent

LigandBDBM107898(CHEMBL373487 | US8604218, 1.049)Copy SMILESCopy InChI

Affinity DataIC50:  604nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI