BDBM10813 3-[2-(prop-2-yn-1-ylamino)ethyl]phenyl N,N-dimethylcarbamate::Phenethylamine deriv. 50a

SMILES CN(C)C(=O)Oc1cccc(CCNCC#C)c1

InChI Key InChIKey=HYXHQZASJISSQN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10813   

TargetCarboxylic ester hydrolase(Horse)
Teva Pharmaceutical Industries

LigandPNGBDBM10813(3-[2-(prop-2-yn-1-ylamino)ethyl]phenyl N,N-dimethy...)
Affinity DataIC50: 210nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Teva Pharmaceutical Industries

LigandPNGBDBM10813(3-[2-(prop-2-yn-1-ylamino)ethyl]phenyl N,N-dimethy...)
Affinity DataIC50: 220nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10813(3-[2-(prop-2-yn-1-ylamino)ethyl]phenyl N,N-dimethy...)
Affinity DataIC50: 2.70E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10813(3-[2-(prop-2-yn-1-ylamino)ethyl]phenyl N,N-dimethy...)
Affinity DataIC50: 2.40E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed