BDBM10832 3-[2-(but-3-yn-2-ylamino)ethyl]phenyl N,N-dimethylcarbamate::Phenethylamine deriv. 54a

SMILES CC(NCCc1cccc(OC(=O)N(C)C)c1)C#C

InChI Key InChIKey=JVYLHZUZDRCHDQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10832   

TargetAcetylcholinesterase(Human)
Teva Pharmaceutical Industries

LigandPNGBDBM10832(3-[2-(but-3-yn-2-ylamino)ethyl]phenyl N,N-dimethyl...)
Affinity DataIC50: 170nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Teva Pharmaceutical Industries

LigandPNGBDBM10832(3-[2-(but-3-yn-2-ylamino)ethyl]phenyl N,N-dimethyl...)
Affinity DataIC50: 240nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10832(3-[2-(but-3-yn-2-ylamino)ethyl]phenyl N,N-dimethyl...)
Affinity DataIC50: 4.40E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10832(3-[2-(but-3-yn-2-ylamino)ethyl]phenyl N,N-dimethyl...)
Affinity DataIC50: 1.00E+6nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed