BDBM109097 US8609852, 3

SMILES Cc1nc(cs1)C#Cc1ccc(nc1)-c1cccc(F)c1

InChI Key InChIKey=IIRMRWPXGDCPBX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109097   

TargetMetabotropic glutamate receptor 5(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM109097(US8609852, 3)
Affinity DataKi:  2.70nM ΔG°:  -11.7kcal/moleT: 25°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails US Patent