BDBM1098 (4R,5R,6R)-Tetrahydro-1,3-bis[(3-cyanophenyl)methyl]-5-hydroxy-4-(2-(4-fluorophenyl)ethyl)-6-(4-fluorophenylmethyl)-2(1H)-pyrimidinone::3-{[(4R,5R,6R)-3-[(3-cyanophenyl)methyl]-6-[2-(4-fluorophenyl)ethyl]-4-[(4-fluorophenyl)methyl]-5-hydroxy-2-oxo-1,3-diazinan-1-yl]methyl}benzonitrile::Tetrahydropyrimidinone deriv. 51
SMILES O[C@@H]1[C@@H](CCc2ccc(F)cc2)N(Cc2cccc(c2)C#N)C(=O)N(Cc2cccc(c2)C#N)[C@@H]1Cc1ccc(F)cc1
InChI Key InChIKey=GEHHNRDORULTOP-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 1098
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 14nM ΔG°: -11.1kcal/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Florida
Curated by ChEMBL
University of Florida
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibitory activity of compound against HIV-1 aspartyl protease.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Florida
Curated by ChEMBL
University of Florida
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Florida
Curated by ChEMBL
University of Florida
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair