BDBM11004 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazole deriv. 1::5-(4-chlorophenyl)-3-(4-methylphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide

SMILES Cc1ccc(cc1)C1=NN(C(C1)c1ccc(Cl)cc1)C(N)=S

InChI Key InChIKey=GJPMHQYGBHVAIX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11004   

TargetAmine oxidase [flavin-containing] B(Bovine)
Sapienza University of Rome

LigandPNGBDBM11004(1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...)
Affinity DataKi:  1.5nM ΔG°:  -12.6kcal/molepH: 7.4 T: 38°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandPNGBDBM11004(1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...)
Affinity DataKi:  31nM ΔG°:  -10.7kcal/molepH: 7.4 T: 38°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed