BDBM1108 (4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis(1H-indazol-6-ylmethyl)-6-(2-phenylethyl)-1,3-diazinan-2-one::(4R,5R,6R)-Tetrahydro-5-hydroxy-1,3-bis[(1H-indazol-6-yl)methyl]-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone::Tetrahydropyrimidinone deriv. 69
SMILES O[C@@H]1[C@@H](CCc2ccccc2)N(Cc2ccc3cn[nH]c3c2)C(=O)N(Cc2ccc3cn[nH]c3c2)[C@@H]1Cc1ccccc1
InChI Key InChIKey=HJBJOSQKBXBTER-CKOYEXALSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 1108
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 0.0600nM ΔG°: -14.5kcal/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0601nMAssay Description:Inhibitory activity of compound against HIV-1 aspartyl protease.More data for this Ligand-Target Pair