BDBM111166 US10556908, Example 18::US9695180, 18
SMILES CN1CCCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc(C)cc2)n2ccnc12
InChI Key InChIKey=KTLPQNVPWYZSDU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 111166
Affinity DataIC50: <50nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMpH: 7.5 T: 25°CAssay Description:10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM NaCl, 5 mM DTT) were preincubated ...More data for this Ligand-Target Pair