BDBM11128 (2S)-2-amino-1-[(2S)-2-[(benzyloxy)methyl]pyrrolidin-1-yl]-3-(4-phenylphenyl)propan-1-one::4-phenylphenylalaninyl proline mimetic 15

SMILES N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N1CCC[C@H]1COCc1ccccc1

InChI Key InChIKey=FNEAEWIAOSSBDK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11128   

TargetDipeptidyl peptidase 4(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11128((2S)-2-amino-1-[(2S)-2-[(benzyloxy)methyl]pyrrolid...)
Affinity DataKi: >1.28E+4nM ΔG°: >-6.67kcal/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed