BDBM11232 N-[(benzyloxy)carbonyl]-O-(tert-butyl)-L-threonyl-N1-((1S,2E)-4-ethoxy-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}but-2-enyl)-L-leucinamide::TG-0203770::TG-0205221 Analogue 4::acs.jmedchem.1c00409_ST.44::ethyl (2E,4S)-4-[(2S)-2-[(2S,3S)-2-{[(benzyloxy)carbonyl]amino}-3-(tert-butoxy)butanamido]-4-methylpentanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
SMILES CCOC(=O)\C=C\[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)OC(C)(C)C
InChI Key InChIKey=PWBQMVUCCVWDEJ-YVSZZSSPSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 11232
Affinity DataKi: 58nM ΔG°: -9.87kcal/molepH: 7.5 T: 25°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
Affinity DataKi: 58nM ΔG°: -9.87kcal/molepH: 6.5 T: 25°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nM ΔG°: -7.94kcal/molepH: 6.5 T: 25°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair