BDBM11261 dipeptidomimetic unsaturated ester 18c::ethyl (2E,4S)-4-[(2S)-2-[(2E)-3-[4-(dimethylamino)phenyl]prop-2-enamido]-3-phenylpropanamido]-5-phenylpent-2-enoate::ethyl (2E,4S)-4-[(N-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-enoyl}-L-phenylalanyl)amino]-5-phenylpent-2-enoate::med.21724, Compound 39

SMILES CCOC(=O)\C=C\[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccc(cc1)N(C)C

InChI Key InChIKey=JWPLKCWYGMPRGX-ZIIPDIQWSA-N

Data  3 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 11261   

TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11261(dipeptidomimetic unsaturated ester 18c | ethyl (2E...)
Affinity DataKi:  520nM ΔG°:  -8.57kcal/mole IC50:  1.00E+3nMpH: 7.0 T: 25°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11261(dipeptidomimetic unsaturated ester 18c | ethyl (2E...)
Affinity DataKi:  520nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11261(dipeptidomimetic unsaturated ester 18c | ethyl (2E...)
Affinity DataKi:  520nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11261(dipeptidomimetic unsaturated ester 18c | ethyl (2E...)
Affinity DataEC50:  180nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11261(dipeptidomimetic unsaturated ester 18c | ethyl (2E...)
Affinity DataEC50:  180nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11261(dipeptidomimetic unsaturated ester 18c | ethyl (2E...)
Affinity DataIC50:  1.00E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed