BDBM11283 2-[(5-cyano-6-oxo-4-phenyl-1,6-dihydropyrimidin-2-yl)sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide::acs.jmedchem.1c00409_ST.776::pyrimidinone-containing compound 20

SMILES N#Cc1c(-c2ccccc2)nc(SCC(=O)Nc2cccc(C(F)(F)F)c2)[nH]c1=O

InChI Key InChIKey=FNZHACBCLXJSBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11283   

TargetReplicase polyprotein 1ab(SARS-CoV)
National Tsing Hua University

LigandChemical structure of BindingDB Monomer ID 11283BDBM11283(2-[(5-cyano-6-oxo-4-phenyl-1,6-dihydropyrimidin-2-...)
Affinity DataIC50: 2.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Tsing Hua University

LigandChemical structure of BindingDB Monomer ID 11283BDBM11283(2-[(5-cyano-6-oxo-4-phenyl-1,6-dihydropyrimidin-2-...)
Affinity DataIC50: 2.00E+5nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed