BDBM113568 US8633204, 315
SMILES COc1ncc(cc1F)-c1cc2c(C)nc(N)nc2n([C@H]2C[C@@H](C2)OCCO)c1=O
InChI Key InChIKey=MQYKSHFHKJXVCJ-JOCQHMNTSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 113568
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 3.11nMpH: 7.4 T: 25°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair