BDBM114419 US20260001886, Compound 59

SMILES CC(C)c1cn(Cc2ccc(S(C)(=N)=O)c(C(F)(F)F)c2)c2nc(C3CC3)nn2c1=O

InChI Key InChIKey=QTOMIEZSACPHJL-UHFFFAOYSA-N

Data  3 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 114419   

LigandChemical structure of BindingDB Monomer ID 114419BDBM114419(US20260001886, Compound 59)
Affinity DataKd:  1.26nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 114419BDBM114419(US20260001886, Compound 59)
Affinity DataEC50:  6.31nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetCarbonic anhydrase 2(Human)
RE Ventures I

US Patent
LigandChemical structure of BindingDB Monomer ID 114419BDBM114419(US20260001886, Compound 59)
Affinity DataKd: >1.00E+8nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetCarbonic anhydrase 1(Human)
RE Ventures I

US Patent
LigandChemical structure of BindingDB Monomer ID 114419BDBM114419(US20260001886, Compound 59)
Affinity DataKd: >1.00E+8nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent