BDBM114612 1-[6-[4-[1-(2-methoxyethyl)pyrazol-4-yl]-1-methyl-5-(5-methyl-1H-indazol-4-yl)imidazol-2-yl]-2-azaspiro[3.3]heptan-2-yl]prop-2-en-1-one::US20260060961, Example 15

SMILES C=CC(=O)N1CC2(CC(c3nc(-c4cnn(CCOC)c4)c(-c4c(C)ccc5[nH]ncc45)n3C)C2)C1

InChI Key InChIKey=ABDSXFXXKGAHKP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 114612   

TargetGTPase KRas [G12C](Human)
Jazz Pharmaceuticals Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 114612BDBM114612(1-[6-[4-[1-(2-methoxyethyl)pyrazol-4-yl]-1-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2026
Entry Details
US Patent