BDBM114764 4-oxo-6-(2- pyrimidin-2- ylazetidin-1- yl)-1-[1-[6- (trifluoromethyl)- 3- pyridyl]ethyl]- 5H- pyrazolo[3,4- d]pyrimidine- 3-carbonitrile::US20260001888, Example 45

SMILES CC(c1ccc(C(F)(F)F)nc1)n1nc(C#N)c2c(=O)[nH]c(N3CCC3c3ncccn3)nc21

InChI Key InChIKey=ZWWXYTMJWVKWLZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 114764   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 114764BDBM114764(4-oxo-6-(2- pyrimidin-2- ylazetidin-1- yl)-1-[1-[6...)
Affinity DataKi:  0.230nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent