BDBM114791 1-[1-(4- cyclopropylphenyl) ethyl]-6- [1-(5-fluoro- pyrimidin-2- yl)propyl- methyl- amino]-4-oxo- 5H- pyrazolo[3,4- d]pyrimidine-3-carbonitrile::US20260001888, Example 68

SMILES CCC(c1ncc(F)cn1)N(C)c1nc2c(c(C#N)nn2C(C)c2ccc(C3CC3)cc2)c(=O)[nH]1

InChI Key InChIKey=IHWSRSPDNBEWBV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 114791   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 114791BDBM114791(1-[1-(4- cyclopropylphenyl) ethyl]-6- [1-(5-fluoro...)
Affinity DataKi:  0.730nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent