BDBM114814 4-oxo-6-(2- (pyrimidin-2- yl)butyl)-1-(1-(6- (trifluoromethyl) pyridin-3- yl)ethyl)-4,5- dihydro-1H- pyrazolo[3,4- d]pyrimidine-3- carbonitrile::US20260001888, Example 89

SMILES CCC(Cc3nc1c(c(C#N)nn1C(C)c2ccc(C(F)(F)F)nc2)c(=O)[nH]3)c4ncccn4

InChI Key InChIKey=MQQWYVBTRXBANK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 114814   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 114814BDBM114814(4-oxo-6-(2- (pyrimidin-2- yl)butyl)-1-(1-(6- (trif...)
Affinity DataKi:  0.240nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent