BDBM118631 US8653263, 284

SMILES Cc1cc(C)nc(N2CC3CN(C(=O)c4cccc(F)c4-c4cc[nH]n4)CC3C2)n1

InChI Key InChIKey=WWMCPSOGOQDQPZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 118631   

TargetOrexin receptor type 2(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 118631BDBM118631(US8653263, 284)
Affinity DataKi:  8nMAssay Description:The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2014
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 118631BDBM118631(US8653263, 284)
Affinity DataKi:  587nMAssay Description:The in vitro affinity of the compounds for the human orexin-1 and orexin-2 receptors was determined by competitive radioligand binding using [3H]SB S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2014
Entry Details
US Patent