BDBM118757 US8674113, 14

SMILES Cn1c(Nc2c(Cl)ccc(CNC(=O)C(C)(C)C)c2Cl)nc2cc(C(=O)NC3CC(F)(F)C3)c(cc12)N1CCC(CC1)C(F)(F)F

InChI Key InChIKey=WROFUPVHFCAUPE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 118757   

TargetProstaglandin E synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM118757(US8674113, 14)
Affinity DataIC50:  1nMpH: 7.4 T: 25°CAssay Description:The aim of this assay is to determine the affinity of a test compound for the mPGES-1 enzyme. 47 μl of recombinant human mPGES-1 (0.5 μg p...More data for this Ligand-Target Pair
In DepthDetails US Patent