BDBM119131 Lometrexol (3)

SMILES Nc1nc2c(c(=O)[nH]1)C[C@@H](CCc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)CN2

InChI Key InChIKey=ZUQBAQVRAURMCL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119131   

TargetBifunctional purine biosynthesis protein ATIC(Human)
The Scripps Research Institute

LigandChemical structure of BindingDB Monomer ID 119131BDBM119131(Lometrexol (3))
Affinity DataKi: >1.00E+5nMAssay Description:Enzyme activity assays of recombinant hGAR Tfase and recombinant hAICAR Tfase were performed as previously described. Kinetics of the enzyme reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMed