BDBM119818 US8691852, 35

SMILES COc1cccc(c1)-c1cc(F)c(Nc2ncc(C)cc2C(O)=O)c(F)c1

InChI Key InChIKey=SYUKBSGBXBRWGY-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119818   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)TBA

LigandBDBM119818(US8691852, 35)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:Inhibition of Homo sapiens (human) dehydroorotate dihydrogenase using 2,6-dichlorophenol-indophenol as substrate after 10 min by spectrophotometric a...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/31/2020
Entry Details Article
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TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)TBA

LigandBDBM119818(US8691852, 35)Copy SMILESCopy InChI

Affinity DataIC50: 12nMpH: 8.0Assay Description:DHODH activity and its inhibition were studied using a chromogen reduction assay with DCIP (2,6-dichlorophenol-indophenol). The substrate oxidation (...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/30/2014
Entry Details
Copy BDB DOIUS Patent

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