BDBM120470 Roche-Dataset for PDE10A, Compound 681::US8703768, 70
SMILES CC(C)(O)CNC(=O)c1ccncc1NC(=O)c1nc(ccc1Nc1cncnc1)C1CC1
InChI Key InChIKey=OPRLZCJBXDOIMR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 120470
Affinity DataIC50: 2.08nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair