BDBM120741 US8703767, 1

SMILES C=CC(=O)Nc1cccc(-c2nc(Nc3ccc(N4CCOCC4)cc3)nc3n[nH]cc23)c1

InChI Key InChIKey=AJRUCFATZODVHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120741   

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandChemical structure of BindingDB Monomer ID 120741BDBM120741(US8703767, 1)
Affinity DataIC50: 45nMT: 2°CAssay Description:Activity of compounds was routinely confirmed using a secondary assay as described herein. The secondary assay was a time resolved-FRET kinase assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandChemical structure of BindingDB Monomer ID 120741BDBM120741(US8703767, 1)
Affinity DataIC50: 79nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent