BDBM121444 US8722709, 48
SMILES Cc1cc(F)ccc1CCc1ccnc(NC(N)=O)c1
InChI Key InChIKey=CXKHFDPOIKOCQS-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 121444
Affinity DataIC50: 4.70nMpH: 7.4Assay Description:The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Displacement of TAMRA-labeled dexamethasone from full-length human mineralocorticoid receptor expressed in baculovirus infected insect cells after 60...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Antagonist activity at Gal4-fused human MR LBD expressed in HEK293T cells assessed as inhibition of aldosterone-induced transactivation activity afte...More data for this Ligand-Target Pair