BDBM12233 AZD0530 analogue 11::N-(2H-1,3-benzodioxol-4-yl)-5-(oxan-4-yloxy)-7-[3-(pyrrolidin-1-yl)propoxy]quinazolin-4-amine::N-1,3-Benzodioxol-4-yl-7-(3-pyrrolidin-1-ylpropoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine

SMILES C(COc1cc(OC2CCOCC2)c2c(Nc3cccc4OCOc34)ncnc2c1)CN1CCCC1

InChI Key InChIKey=IWGJMDXPSOGADO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12233   

LigandPNGBDBM12233(N-(2H-1,3-benzodioxol-4-yl)-5-(oxan-4-yloxy)-7-[3-...)
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed
LigandPNGBDBM12233(N-(2H-1,3-benzodioxol-4-yl)-5-(oxan-4-yloxy)-7-[3-...)
Affinity DataIC50: 100nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed