BDBM12237 AZD0530 analogue 15::N-(5-chloro-2H-1,3-benzodioxol-4-yl)-5-(oxan-4-yloxy)-7-[3-(pyrrolidin-1-yl)propoxy]quinazolin-4-amine

SMILES Clc1ccc2OCOc2c1Nc1ncnc2cc(OCCCN3CCCC3)cc(OC3CCOCC3)c12

InChI Key InChIKey=HLILQABBLFGERM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12237   

LigandPNGBDBM12237(N-(5-chloro-2H-1,3-benzodioxol-4-yl)-5-(oxan-4-ylo...)
Affinity DataIC50: 4nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed
LigandPNGBDBM12237(N-(5-chloro-2H-1,3-benzodioxol-4-yl)-5-(oxan-4-ylo...)
Affinity DataIC50: 2.50E+3nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed