BDBM12239 AZD0530 analogue 17::N-(2,3-Dihydro-1,4-benzodioxin-5-yl)-7-(2-pyrrolidin-1-ylethoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine::N-(2,3-dihydro-1,4-benzodioxin-5-yl)-5-(oxan-4-yloxy)-7-[2-(pyrrolidin-1-yl)ethoxy]quinazolin-4-amine dihydrochloride

SMILES C(CN1CCCC1)Oc1cc(OC2CCOCC2)c2c(Nc3cccc4OCCOc34)ncnc2c1

InChI Key InChIKey=MNYUDSXBPUCGII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12239   

LigandPNGBDBM12239(N-(2,3-dihydro-1,4-benzodioxin-5-yl)-5-(oxan-4-ylo...)
Affinity DataIC50: 50nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed
LigandPNGBDBM12239(N-(2,3-dihydro-1,4-benzodioxin-5-yl)-5-(oxan-4-ylo...)
Affinity DataIC50: 85nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed