BDBM12244 AZD0530 analogue 22::N-(2-chloro-5-methoxyphenyl)-6,7-dimethoxyquinazolin-4-amine

SMILES COc1ccc(Cl)c(Nc2ncnc3cc(OC)c(OC)cc23)c1

InChI Key InChIKey=RDRQLLSZGBPUMT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12244   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM12244(N-(2-chloro-5-methoxyphenyl)-6,7-dimethoxyquinazol...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant c-SRC catalytic domain using pEY (4:1) as substrate incubated for 30 mins in presence of ATP by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM12244(N-(2-chloro-5-methoxyphenyl)-6,7-dimethoxyquinazol...)
Affinity DataIC50: 250nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed