BDBM12247 AZD0530 analogue 25::N-(5-chloro-2H-1,3-benzodioxol-4-yl)-7-[3-(4-methylpiperazin-1-yl)propoxy]-5-(oxan-4-yloxy)quinazolin-4-amine

SMILES CN1CCN(CCCOc2cc(OC3CCOCC3)c3c(Nc4c5OCOc5ccc4Cl)ncnc3c2)CC1

InChI Key InChIKey=NNTCPBYVAUSUOH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12247   

LigandPNGBDBM12247(N-(5-chloro-2H-1,3-benzodioxol-4-yl)-7-[3-(4-methy...)
Affinity DataIC50: 4nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed
LigandPNGBDBM12247(N-(5-chloro-2H-1,3-benzodioxol-4-yl)-7-[3-(4-methy...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed