BDBM12252 AZD0530 analogue 30::N-(5-Chloro-1,3-benzodioxol-4-yl)-5-isopropoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine::N-(5-chloro-2H-1,3-benzodioxol-4-yl)-5-(propan-2-yloxy)-7-[3-(pyrrolidin-1-yl)propoxy]quinazolin-4-amine dihydrochloride

SMILES CC(C)Oc1cc(OCCCN2CCCC2)cc2ncnc(Nc3c4OCOc4ccc3Cl)c12

InChI Key InChIKey=DVAZOVKPBNZYLL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12252   

LigandPNGBDBM12252(AZD0530 analogue 30 | N-(5-Chloro-1,3-benzodioxol-...)
Affinity DataIC50:  1.20E+3nMAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM12252(AZD0530 analogue 30 | N-(5-Chloro-1,3-benzodioxol-...)
Affinity DataIC50: <4nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed