BDBM12264 AZD0530 analogue 42::N-(6-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(oxan-4-yloxy)quinazolin-4-amine

SMILES CN1CCN(CCOc2cc(OC3CCOCC3)c3c(Nc4c(Cl)ccc5OCCOc45)ncnc3c2)CC1

InChI Key InChIKey=IOXLERDREGOQSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12264   

LigandPNGBDBM12264(N-(6-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-7-[2...)
Affinity DataIC50: 65nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed