BDBM122673 US8735386, I-143

SMILES COc1ccc(-c2c-3c(CCc4cnc(Nc5ccc(cc5OC)C(=O)NC5CCN(C)CC5)nc-34)nn2C)c(Cl)c1

InChI Key InChIKey=LGDCGOHLXJYDNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 122673   

TargetInsulin-like growth factor 1 receptor(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM122673(US8735386, I-143)
Affinity DataIC50: 0.400nMpH: 7.4Assay Description:The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent