BDBM122749 US8735386, I-219

SMILES CC(C)n1ccc(Nc2ncc3CCc4nn(C)c(Cc5ccccc5Cl)c4-c3n2)n1

InChI Key InChIKey=KVKAHMTVUCUJHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 122749   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM122749(US8735386, I-219)
Affinity DataIC50:  5nMpH: 7.4Assay Description:The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...More data for this Ligand-Target Pair
In DepthDetails US Patent