BDBM123056 US8742134, (3)::US8742134, (8)

SMILES C[N+]1(C)C2CCC1[C@H](C2)OC(=O)[C@](O)(C1CCCC1)c1ccccc1

InChI Key InChIKey=GIQCKBPBJOZAKR-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 123056   

TargetMuscarinic acetylcholine receptor M3(Human)
Theron Pharmaceuticals

US Patent
LigandPNGBDBM123056(US8742134, (8) | US8742134, (3))
Affinity DataKi:  0.180nM ΔG°:  -13.2kcal/mole IC50: 0.25nMT: 2°CAssay Description:Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Theron Pharmaceuticals

US Patent
LigandPNGBDBM123056(US8742134, (8) | US8742134, (3))
Affinity DataKi:  26nM ΔG°:  -10.2kcal/mole IC50: 36nMT: 2°CAssay Description:Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent