BDBM123057 US8742134, (4)::US8742134, (5)::US8742134, (6)

SMILES C[N+]1(C)C2CCC1[C@H](C2)OC(=O)[C@@](O)(C1CCCC1)c1ccccc1

InChI Key InChIKey=GIQCKBPBJOZAKR-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 123057   

TargetMuscarinic acetylcholine receptor M3(Human)
Theron Pharmaceuticals

US Patent
LigandPNGBDBM123057(US8742134, (5) | US8742134, (6) | US8742134, (4))
Affinity DataKi:  0.220nM ΔG°:  -13.0kcal/mole IC50: 0.300nMT: 2°CAssay Description:Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Theron Pharmaceuticals

US Patent
LigandPNGBDBM123057(US8742134, (5) | US8742134, (6) | US8742134, (4))
Affinity DataKi:  1.5nM ΔG°:  -11.9kcal/mole IC50: 2.10nMT: 2°CAssay Description:Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Theron Pharmaceuticals

US Patent
LigandPNGBDBM123057(US8742134, (5) | US8742134, (6) | US8742134, (4))
Affinity DataKi:  2.10nM ΔG°:  -11.7kcal/mole IC50: 2.90nMT: 2°CAssay Description:Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent