BDBM123654 US8748618, AI-4-57 (or) LD-1-11C::US8748618, LD-1-127::US8748618, NCI- 320656

SMILES OCc1ccc2nc([nH]c2c1)-c1ccccn1

InChI Key InChIKey=RICDCKXIDGEMKB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 123654   

TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123654(US8748618, AI-4-57 (or) LD-1-11C | US8748618, LD-1...)
Affinity DataIC50:  1.60E+4nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123654(US8748618, AI-4-57 (or) LD-1-11C | US8748618, LD-1...)
Affinity DataIC50:  2.00E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123654(US8748618, AI-4-57 (or) LD-1-11C | US8748618, LD-1...)
Affinity DataIC50:  2.60E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails US Patent