BDBM123891 US8754113, I-1-85::US9169240, 24
SMILES NS(=O)(=O)NCc1nnc(Cc2nc3ccc(cc3s2)-c2ccccc2)o1
InChI Key InChIKey=YGZCJOQFMJZVDF-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 123891
Affinity DataIC50: 5nMT: 37°CAssay Description:After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMpH: 8.0Assay Description:The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 μL of assay buffer (50 mM HEPES pH 8.0, 50...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human endothelial lipase using HDL as substrate measured after 4 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...More data for this Ligand-Target Pair