BDBM124286 US8759537, 23

SMILES Cn1c(Nc2c(Cl)ccc(CNC(=O)C(C)(C)C)c2Cl)nc2cc(C(=O)Nc3cc(F)cc(Cl)c3)c(F)cc12

InChI Key InChIKey=KMQVMHMHNSKPNN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124286   

TargetProstaglandin E synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM124286(US8759537, 23)
Affinity DataIC50:  1nMpH: 7.4 T: 25°CAssay Description:The aim of this assay is to determine the affinity of a test compound for the mPGES-1 enzyme. 47 ul of recombinant human mPGES-1 (0.5 ug protein/wel...More data for this Ligand-Target Pair
In DepthDetails US Patent