BDBM125901 US8765727, 4
SMILES Clc1cnc2Nc3cccc(c3)C(=O)Nc3cccc(CNc1n2)c3
InChI Key InChIKey=WKFDYXPIKYJBDD-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 125901
Affinity DataIC50: >1.00E+4nMpH: 7.8Assay Description:HTRF kinase assay: 40 μL reactions were run in black 384 well polystyrene plates in assay buffer (50 mM Tris, pH 7.8, 100 mM NaCI, 0.1 mg/mL BSA...More data for this Ligand-Target Pair
Affinity DataIC50: 96nMpH: 7.8 T: 25°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:TYK2 assays described by James E. Thompson et. al, Photochemical preparation of a pyridone containing tetracycle: A JAK protein kinase inhibitor, Bio...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMpH: 7.8 T: 25°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
Affinity DataIC50: 104nMpH: 7.8 T: 25°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair