BDBM126165 US8779142, Comparative Example 2::US9120780, Comparative Example 2

SMILES COc1cccc2n(ccc12)-c1ccc(C(N)=O)c(NC2CCC(O)CC2)c1

InChI Key InChIKey=MHWGEXNUPBAAKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 126165   

TargetHeat shock protein HSP 90-alpha(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM126165(US8779142, Comparative Example 2 | US9120780, Comp...)
Affinity DataIC50: 1.00E+5nMpH: 7.5Assay Description:The HSP90-binding activity was measured by an AlphaScreen competitive assay system. The purified HSP90 solution was diluted with a binding buffer (50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetHeat shock protein HSP 90-alpha(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM126165(US8779142, Comparative Example 2 | US9120780, Comp...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The HSP90-binding activity was measured by an AlphaScreen competitive assay system. The purified HSP90 solution was diluted with a binding buffer (50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent