BDBM12626 (2S,5R)-1-[(2S)-2-amino-4-methylpentanoyl]-5-ethynylpyrrolidine-2-carbonitrile::(2S,5R)-5-ethynyl-1-L-leucylpyrrolidine-2-carbonitrile::C5-substituted pyrrolidine 14

SMILES CC(C)C[C@H](N)C(=O)N1[C@H](CC[C@H]1C#N)C#C

InChI Key InChIKey=XXTBOOXAFXMJIZ-SRVKXCTJSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12626   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM12626((2S,5R)-1-[(2S)-2-amino-4-methylpentanoyl]-5-ethyn...)
Affinity DataKi:  8nM ΔG°:  -10.9kcal/molepH: 7.5 T: 22°CAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed