BDBM126523 US8778951, 334

SMILES CC1(CNc2nc(-c3cc(N[C@H]4CC[C@H](NC5(C)OCCO5)CC4)ncc3Cl)ccc2F)CCOCC1

InChI Key InChIKey=VAWGLAQKVMITLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126523   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 126523BDBM126523(US8778951, 334)
Affinity DataIC50: 0.00100nMAssay Description:Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent