BDBM126705 US8778970, 4-11

SMILES Cl.OC(=O)COc1cc(CC2CCN(CCc3ccc4occc(=O)c4c3)CC2)ccc1Br

InChI Key InChIKey=HCGLBMZUWBYWLK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 126705   

Target5-hydroxytryptamine receptor 1A(Human)
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM126705(US8778970, 4-11)
Affinity DataKi:  67nM ΔG°:  -9.78kcal/moleT: 2°CAssay Description:The experiment was carried out according to the method of Yabuuchi et al. [Yabuuchi K. et al., Biogenic Amines, 18, 319-328 (2004)]. 50 ul of [3H] 8-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Dainippon Sumitomo Pharma

US Patent
LigandPNGBDBM126705(US8778970, 4-11)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:[3H] citalopram binding was assayed according to the method of Owens et al. [Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997)]. Specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent