BDBM126989 US8785459, 64

SMILES COc1ccc(cc1)-c1ccc2ncnc(Nc3cccc(O)c3)c2c1

InChI Key InChIKey=YOVFBIUTXSMTJA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 126989   

TargetSerine/threonine-protein kinase B-raf(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM126989(US8785459, 64)
Affinity DataIC50: 62.4nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM126989(US8785459, 64)
Affinity DataIC50: 105nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM126989(US8785459, 64)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent