BDBM126997 US8785459, 72

SMILES CS(=O)(=O)Nc1cccc(c1)-c1ccc2ncnc(Nc3cccc(O)c3)c2c1

InChI Key InChIKey=LIUVILQGTPHLCP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 126997   

TargetSerine/threonine-protein kinase B-raf(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM126997(US8785459, 72)
Affinity DataIC50: 73.8nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM126997(US8785459, 72)
Affinity DataIC50: 90nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM126997(US8785459, 72)
Affinity DataIC50: 861nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent